“Mistakeproofing” is the use of any device or method that either makes it impossible for an error to occur or makes the error immediately obvious once it has occurred. The objective of mistakeproofing is to reduce or eliminate the occurrence of errors, as they cause resource waste and defects. Mistakeproofing includes both labor and management: everyone can help identify opportunities to reduce or eliminate errors by applying mistakeproofing tools and practices through creative problem-solving. The authors explore how mistakeproofing applies in construction to reduce incidents and worker injuries, which are substantial sources of waste in the industry as they interrupt production, cost lost workdays, or result in other harm.